Nutrient-dependent growth of NIH3T3 and NIH3T3 K-ras cell lines.

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GSE29962

Mus musculus

28 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Expression profiling of normal NIH3T3 and transformed NIH3T3 K-ras cell lines grown for 72 hours in optimal glucose availability (25 mM glucose) or low glucose availability (1 mM). Low glucose induces apoptosis in transformed cells as compared to normal ones.

PubMed ID

21847114

Publication Title

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth.

Total Samples

Submitter’s Institution

University of Milano-Bicocca

Authors

Gaglio D, Metallo CM, Gameiro PA, Hiller K, Danna LS, Balestrieri C, Alberghina L, Stephanopoulos G, Chiaradonna F

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-29962

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